Nationwide organ sharing using HLA typing
نویسندگان
چکیده
منابع مشابه
A glow of HLA typing in organ transplantation
The transplant of organs and tissues is one of the greatest curative achievements of this century. In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the main goal of the immune response is the MHC (major histocompatibility complex) molecules expressed on the surface of donor cells. Cell surface molecules that induce an anti...
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It has been more than ten years since the first Human Leukocyte Antigen (HLA) matching for Fanconi anemia was reported, allowing successful haemopoietic reconstitution in affected sibling by transplantation of stem cells obtained from HLA-matched offspring (Verlinsky et al., 2000; Verlinsky et al., 2001). Preimplantation Genetic Diagnosis (PGD) in combination with HLA matching is being used to ...
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After in vitro mixed lymphocyte culture, cytotoxic lymphocytes develop which have specificity for components of the main histocompatibility complex (MHC) 1 of the stimulating lymphocyte population (1, 2). The effector cells were found to be directed mainly against class I histocompatibility antigens, that is, the H2-K and H2D antigens in the mouse (3), and the HLA-A or HLA-B antigens in man (4)...
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Dept. of Biology, Oncology and Genetics, Univ. Genova, Largo R. Benzi 10, 16132 Genova Italy Advanced Biotechnologies Center, Largo R. Benzi 10, 16132 Genova Italy Dept. of Computer Science, Univ. Pisa, Corso Italia 40, 56125 Pisa Italy National Institute for the Physics of Matter, Via Dodecaneso 33, 16146 Genova Italy Dept. of Computer and Information Science, Univ. Genova, Via Dodecaneso 35, ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1991
ISSN: 0085-2538
DOI: 10.1038/ki.1991.64